Written answers

Monday, 8 September 2025

Photo of David CullinaneDavid Cullinane (Waterford, Sinn Fein)
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2088. To ask the Minister for Health whether she has considered routine CA-125 testing; and if she will make a statement on the matter. [44638/25]

Photo of Jennifer Carroll MacNeillJennifer Carroll MacNeill (Dún Laoghaire, Fine Gael)
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CA-125 is a tumour marker associated with ovarian cancer. A blood test for CA-125 can be carried out in primary care, as part of the assessment of an individual with possible signs/ symptoms of ovarian cancer. It is also used to monitor response to treatment for ovarian cancer, including follow up to look for recurrence.

The National Cancer Control Programme has advised that CA-125 can be raised in other conditions, including endometriosis, pelvic inflammatory disease and pregnancy, and that it is also possible for CA-125 levels to be normal in a patient who has ovarian cancer, particularly in the earlier stages.

There are several criteria which a test should meet for consideration as a screening test. The National Cancer Control Programme has advised that CA-125 does not meet these criteria as it can be raised for reasons other than the presence of ovarian cancer.

The National Screening Advisory Committee advises the Minister and Department of Health on all new proposals for population-based screening programmes and revisions to existing programmes and outlines criteria for an effective screening test/programme here:

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