Leo Varadkar (Dublin West, Fine Gael) | Oireachtas source

It is always open to the manufacturer to submit new evidence, a new reduced price, or both, or, as Senator John Crown has suggested, there is always the possibility of a cost-sharing arrangement whereby the HSE would only reimburse the cost of medicine for those in whom it was proved to work. These are all options, but we need to start to put pressure on the industry to come up with and agree to such arrangements, rather than always putting pressure on the taxpayer to pay more and more.