Leo Varadkar (Dublin West, Fine Gael) | Oireachtas source

The Deputy makes a valid point on orphan drugs and ultra-rare diseases and I recognise his expertise in this matter. No matter what we do with orphan drugs or ultra-rare diseases, we need some mechanism to establish whether the medicine is effective and what represents a fair price as we need to ensure that patients receive drugs which are effective and which taxpayers can afford.

See this speech in context