Professor William Gallagher:

In the cancer space, I commented in my opening statement that we have made tremendous progress in understanding the causes of cancer, but also in developing novel therapeutic approaches, particularly following the formation of the all-Ireland cancer consortium, which had a major catalytic effect on the clinical trials ecosystem on the island of Ireland. It also had specific knock-on impacts in terms of improvement in survival.

I will call on Professor Hanna to comment on that. When we think about outcomes, it is not just purely about survival, although that it is important, but also the quality of life of an individual post their treatment. Ms Gaynor can come in on that.