Dr. Jerome Coffey:

I will make a general point, and I do not have the expertise to give a specific number or tight range. I will not put anything forward on that. What I will say is that a point I made earlier is it is probably appropriate to state that in any redesign or review of any of the patient information material, it is important that we get the patient's voice and the patient representative's voice in the room when it is being drafted. I cannot say what-----